COVID-19 updates: The newest preprint new study reveals XBB.1.16 Omicron variant, which is behind the COVID-19 surge in India and also will unfold worldwide in the close to future, has an efficient reproductive quantity (Re) 1.27 and 1.17-fold larger respectively than XBB.1 and XBB.1.5, suggesting that XBB.1.16 will unfold worldwide in the close to future.
“At the end of March 2023, XBB.1.16, a SARS-CoV-2 omicron XBB subvariant, emerged and was detected in various countries. Compared to XBB.1.5, XBB.1.16 has two substitutions in the S protein: E180V is in the N-terminal domain, and T478K in the receptor-binding domain (RBD). We first show that XBB.1.16 had an effective reproductive number (Re) that was 1.27- and 1.17-fold higher than the parental XBB.1 and XBB.1.5, respectively, suggesting that XBB.1.16 will spread worldwide in the near future.” the study said.
XBB.1.16 beneath WHO monitoring:
“In fact, the WHO classified XBB.1.16 as a variant under monitoring on March 30, 2023. Neutralization assays demonstrated the robust resistance of XBB.1.16 to breakthrough infection sera of BA.2 (18-fold versus B.1.1) and BA.5 (37-fold versus B.1.1). We then used six clinically-available monoclonal antibodies and showed that only sotrovimab exhibits antiviral activity against XBB subvariants, including XBB.1.16. Our results suggest that, similar to XBB.1 and XBB.1.5, XBB.1.16 is robustly resistant to a variety of anti-SARS-CoV-2 antibodies,” it learn additional.
“Our multiscale investigations suggest that XBB.1.16 that XBB.1.16 has a greater growth advantage in the human population compared to XBB.1 and XBB.1.5, while the ability of XBB.1.16 to exhibit profound immune evasion is comparable to XBB.1 and XBB.1.5.” it stated.
Health Ministry overview assembly:
Union Health Minister Dr Mansukh Mandaviya chaired a overview assembly with well being ministers of all states and Union Territories by video conferencing on April 7.
Mandaviya requested all states to remain alert and stay ready for the administration of the illness.Mandaviya additional urged the State Health Ministers to conduct mock drills of all hospital infrastructure on April 10 and 11 and overview the well being preparedness with district administrations and well being officers on April 8 and 9.
(With ANI inputs)
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