Viruses in Cambodian bird flu cases identified as endemic clade

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Viruses in Cambodian bird flu cases identified as endemic clade


Ducks swim in a pond in a Snoa village farm outdoors Phnom Penh, Cambodia, Thursday, February 23, 2023. An 11-year-old lady in Cambodia has died from bird flu in the nation’s first identified human H5N1 an infection since 2014, well being officers mentioned, Wednesday, February 22, 2023.
| Photo Credit: AP

The viruses that contaminated two folks in Cambodia with H5N1 avian influenza have been identified as an endemic clade of bird flu circulating in the nation, the U.S. Centers for Disease Control and Prevention (CDC) mentioned.

The cases reported final week had raised considerations they have been brought on by a brand new pressure of H5N1, clade 2.3.4.4b, which emerged in 2020 and has induced file numbers of deaths amongst wild birds and home poultry in current months.

But work thus far suggests this isn’t the case.

Preliminary genetic sequencing carried out in Cambodia led its well being ministry to determine the viruses as H5 clade 2.3.2.1c, which has circulated in Cambodia amongst birds and poultry for a few years and has sporadically induced infections in folks, the CDC mentioned in an announcement on Saturday.

“Yes, this is an older clade of avian influenza that had been circulating around the region for a number of years and while it has caused human infections in the past, it has not been seen to cause human-to-human transmission. However, that doesn’t mean that the threat is any less,” mentioned Erik Karlsson, director of the National Influenza Center of Cambodia and performing head of virology on the Institut Pasteur du Cambodge, which sequenced the virus.

He added that the response wanted to be coordinated and swift to stop any additional unfold and to restrict publicity to any widespread supply.

An investigation into the supply and to detect any further cases is ongoing, the CDC mentioned, including that thus far there had been no indication of person-to-person unfold.

Cambodia examined not less than 12 folks for the H5N1 pressure final week, after an 11-year-old lady died from the virus in the primary identified transmission to people in the nation in practically a decade.

The sufferer’s father, who was a part of a bunch the lady had been in contact with in a province east of the capital Phnom Penh, examined optimistic for the virus however didn’t exhibit any signs, Cambodia’s Health Minister Mam Bunheng had mentioned in an announcement on Friday.

Only the lady’s case has been sequenced and the daddy’s case continues to be being labored on, Karlsson mentioned.

The World Health Organization mentioned it’s working with Cambodian authorities following the cases, describing the state of affairs as worrying as a result of current rise in cases in birds and mammals.



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