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Why It Matters | Does BCG vaccine work for Covid-19 infection?

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Why It Matters | Does BCG vaccine work for Covid-19 infection?


The BCG vaccine administered to forestall tuberculosis didn’t present any vital safety towards Covid-19 to healthcare employees. Representative picture.
| Photo Credit: Ramalingam B. Jothi/The Hindu

What are the info: The BCG vaccine, sometimes administered to forestall tuberculosis, didn’t present any vital safety towards Covid-19 an infection to healthcare employees, a brand new research stated. Published within the New England Journal of Medicine, the research’s outcomes said that 14.7% of the members who obtained the bacillus Calmette-Guerin (BCG) vaccine confirmed signs of Covid-19 an infection. In comparability, 12.3% of the members within the placebo group confirmed indicators of Covid-19 an infection. Five members from every group had been hospitalised as a result of Covid-19 and one participant from the placebo group succumbed to the an infection.

Also Read | BCG vaccine: 100 years and counting

What is the context?

  • The scientific trial to repurpose the BCG vaccine towards Covid-19 began throughout the early days of the pandemic when there have been fewer methods to deal with Covid-19.
  • The BCG vaccine has existed for over 80 years and is a part of India’s Universal Immunisation Programme.
  • The vaccine, containing weakened strains of Mycobacterium tuberculosis, is run to combat towards tuberculosis, meningitis and different respiratory tract infections, in response to one other research.
  • The present research was presupposed to have 10,000 members from 5 nations and proceed for 12 months, however was stopped as soon as mRNA vaccines had been developed.
  • The paper reported the outcomes of a trial the place 4,000 adults had been noticed over six months. 

Also Read | How the COVID-19 pandemic altered the vaccine story in India 

Why does it matter?

  • While the research proved that the BCG vaccine “did not reduce the risk of Covid-19”, it might be unwise to discard the consequences of the vaccine in different situations, scientists stated. 
  • “The conclusion of our trial — that B.C.G. does not protect health care workers against mild or moderate Covid — is true,” Dr. Nigel Curtis, the trial’s principal investigator, informed The New York Times.
  • “This doesn’t tell us anything about the ability to protect people in other age groups against infections. BCG is still a very important concept in infants,” he added. 
  • He additionally famous that evaluation from the info collected throughout the trial remains to be happening and that the vaccine’s results might change relying on the virus or bacterium to which it’s uncovered.



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